For most jets the best speed/range is between 20,000 - 25,000.
Take the Saab J-29F I just finished with
This test was done in level flight, no weather, and the after burner on the whole time. Note that the range numbers are not including the distance traveled from the airport to get up to altitude. They still are reasonably close and demonstrate the trade off of altitude.
Alt ---------------TAS---------------Range----------Sustained Mach
10,000------------619---------------728-----------------.97
15,000------------602---------------850-----------------.97
20,000------------597---------------975-----------------.97
25,000------------584---------------1140----------------.97
30,000------------570---------------1360----------------.97
35,000------------557---------------1640----------------.96
40,000------------548---------------2021----------------.954
You lose a little over 20 kts of true air speed at 20,000 but gain 247 nm of range.
As you go up the speed drops off more with the range extending. At 35,000 it can no longer maintain .97 mach in level flight.
At 10,000 the fuel burn is 3729 PPH with the burner on and 2773 with it off.
At 40,000 the fuel burn is 1071 PPH on the burner and 764 with it off.
Speeds and ranges can vary by aircraft but the best trade off is in the mid range. From there you can always adjust. If you don't need the range go low to use the speed. However sometimes you can grab a nice tail wind up high. From South Korea to Japan I went up to 34,000 I did not need to or want to but the wind was 160kts directly on the tail (I got the screen shot to prove it
)
As for the Duenna here is how it is fixed.
Start up flight simulator make sure all of your realism settings are correct sometimes they need nudged. I once had that problem and it was the sliders at 99% not 100%. You could not tell by looking at them.
Load up at a airstrip in your local time zone making sure you have real world updates set.
Save this flight as your default flight.
Shut flight simulator off and start it again make sure all the changes are the same you should be good to go.
I will be on TS tonight if you want to stop by and work on it.