F2 is, as far as I know, the basic work-around keyboard command as most throttles didn't exist or have the physical ability to 'reverse' (pull back and over a stop to go into reverse -pitch, not prop rotation of course.). At one time apparently only jets & turboprops could have reverse thrust but thanks to a couple of bright guys it was found how to do it with piston a/c. (greg Pepper et al?)
I've seen references that the X-52 pro has a configurable detent to facilitate the same, but I dunno - maybe also the Saitek Yoke's throttle setup.
I'd have to pass to a builder or two for the answer re: individual models but I can't see why it couldn't be enabled somehow