Still using MS Vista ehh?
People are running CFS2 on WIN 7, 8 & even 10. I think the only compromise most users on newer OS experience is you need to run in windowed mode.
I've never heard of any MS update stopping CFS2 working. This sim doesn't even put anything to the registry (like FS9 & later iterations), & can be run straight from a USB stick if you have to.