Why do the high altitude numbers look odd? This is a supercharged 1700 cubic inch 14 cylinder engine.
Odd in that you can get 247kias (over 400tas @ 35000msl) with only
14" of manifold pressure.
As I see it, when you start changing other numbers to compensate for inaccurate engine output, other less than obvious performance parameters get screwed up. Engine output is relatively easy to adjust and doesn't depend all that much on other airframe variables, so I believe it should be the FIRST thing to be tuned. I don't believe your aversion to virtual engine tuning makes sense.
I don't believe my method makes sense either.. lol But the simplicity of the MSFS model makes all of this an experiment, at best.
One way or another, if you're concerned about accurate
in-flight , you're gonna have to start tweaking for it. Knowing that your engine itself is accurate, but the model won't perform realistically, defeats the whole purpose. Standing on a stack of data that proves the engine power curve is good means nothing if the airplane can't get airborne, AT the proper airspeed, using up the proper amount of runway.. or worse.. leaps off the ground well before it should at something other than V3.. or climbs ridiculously fast (or slow), or is capable of jet-like airspeed at cruise (or is too slow)and if your engine gauges aren't returning accurate data for what your asking the airplane to do, it gets even messier.
I've found, that if you don't play around "inside" of the engine, the other stuff is more achievable... especially gauge readings (ala MP).
Sure, you want to start with something close, "inside" the engine, but if you venture into air-file tables in search of an accurate engine, you're making the actual performance envelope harder to achieve.
I wish you didn't have to play with stuff like wing-effiency, prop-pitch, drags, etc.. when trying to mate takeoff performance to cruise performance (and everything in between), but you really have no choice. It would be wonderful if you could compartmentalize it all.. make a good engine.. make a geometrically/aerodynamically accurate air-frame and just "bolt" them together, and get predictable results.. but that aint gonna happen. I advise you to keep the engine "stock" air-file wise, until you get the performance right.. then (if you really wanna re-open the tweaking cycle), try to "realize" the engine in its own right. Just know that you'll have quite a task getting the takeoff/climb/cruise numbers back to where you want them, not to mention major skewing in gauge readings...
I'm just sharing hard-earned experrience, and truly do respect those willing to strive for realism.. ...and I'm realizing that these topics can get argumentative.. so I'll step aside unless asked for input.