Alrighty, these aircraft are all about hauling heavy stuff to faraway places.
How about...50 tonnes of hardware, Frankfurt - Tel Aviv?
Absent any better ideas, I used the fuel calculator in the sim, which thought 70,000lbs would do, for a journey of just under 4 hours.
This would be well under MTOW, so I put in 100,000lbs of fuel, and loaded 75 tonnes of Big Stuff.
It climbed out of EDDF at 1500fpm, which I think may be a little optimistic for the weight. We cruised along at 30,000ft admiring the scenery over Turkey en route.
Then: calamity!
The journey is 1,500 nm so if 4 hours were correct that meant averaging nearly 375 kts.
I wasn't doing anywhere near that, and a quick look at the fuel gauge showed...we were out of fuel.
Luckily in a simulator you can just add a bit while no-one is watching, and hope for an airstart.
I can report that this bird glides serenely.
At 22,000ft I got E1 going, and the others followed.
A little under five and a half hours after liftoff, and now well into evening, we were cleared into Ben Gurion (Curses! Night screenshot!)
It becomes clear that for this model to have any meaning, it will need a decent FMC and all that goes with it.