Essentially, the Nieuport 48 was a 5/6 scale version of the Nieuport 42. The prototype Nieuport 48 was a parasol monoplane powered by a 400-hp Hispano-Suiza 12 Jb, while the second prototype (Nieuport 48 bis) used a 500-hp Hispano-Suiza 12 Hb. Both engines had a the 12 cylinders in a “V” shaped arrangement and used a Regy-Sabbah propeller.
The first Nieuport 48 was used for static testing, while the second was tested at Villacoublay by adjudant Millo from May to August 1927. The Nieuport 48 benefited from the concentration in mass due to the smaller airframe and the elevators and rudders were enlarged. The ailerons occupied the entire trailing edge of the wing. The third aircraft was the Nieuport 48bis which had the 500-hp Hispano-Suiza 12 Hb. By this time the lightweight fighter program had proved to be unsuccesful, failing to yield a single useful aircraft which compared poorly with types already in service; the Nieuport 48 series being no exception. The second Nieuport 48 ended its’ days as a trainer at Etampes used to train military pilots who would be participating in the Schneider Cup races.
The Nieuport 48bis was tested by Capitaine Joublin and on its’ third flight the wing struts became deformed, moving back 10 centimeters. After being repaired it was finally struck off charge at Villacoublay in early 1928. Redesignated the Ni-D 481 when it was fitted with a 300-hp Lorraine 9 Na engine, it was subsequently used as an aerobtic trainer and carried registration F-AJTC. It was struck of the civil register in 1936.