Yes. I'll give you an example. I like to fly the Ford Tri-Motor, so I have the lever set on top of the CH Yoke assigned to a 3rd engine (Throttle, prop, fuel). I usually remap the Yoke's lever set to the engine on the nose of the Tri-Motor, then have the throttles set on the CH Throttle Quad for the left and right engines. Makes turning while taxiing a bit easier.